Handling nested Tmux sessions

I usually like to use tmux locally, and on word (my VPS) I run a tmux session to have both my website and the Minecraft server perpetually running.

The problem arises when trying to use tmux keybinds, where I am in a tmux session locally, SSH into a VPS I own, and open that tmux session. The key combinations do not work, however, I learned if I pressed the prefix combination <C-b> twice, or <C-b-b>, it executes the keybind in the nested session!